Wellness Database: PMS
PMS refers to a wide range of symptoms occuring in women prior to menstruation. It may be less common in women taking Vitamin B supplements.
Krill Oil Effective in Treating PMS
PRIMARY OBJECTIVE: To evaluate the effectiveness of Neptune Krill Oil (NKO) for the management of premenstrual syndrome and dysmenorrhea.
SECONDARY OBJECTIVE: To compare the effectiveness of NKO for the management of premenstrual syndrome and dysmenorrhea with that of omega-3 fish oil.
METHODS/ DESIGN: Double-blind, randomized clinical trial.
SETTING: Outpatient clinic.
PARTICIPANTS: Seventy patients of reproductive age diagnosed with premenstrual syndrome according to the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised (DSM-III-R).
INTERVENTIONS: Treatment period of three months with either NKO or omega-3 fish oil.
OUTCOME MEASURES: Self-Assessment Questionnaire based on the American College of Obstetricians and Gynecologists (ACOG) diagnostic criteria for premenstrual syndrome and dysmenorrhea and number of analgesics used for dysmenorrhea.
RESULTS: In 70 patients with complete data, a statistically significant improvement was demonstrated among baseline, interim, and final evaluations in the self assessment questionnaire (P < 0.001) within the NKO group as well as between-group comparison to fish oil, after three cycles or 45 and 90 days of treatment. Data analysis showed a significant reduction of the number of analgesics used for dysmenorrhea within the NKO group (comparing baseline vs. 45- vs. 90-day visit). The between-groups analysis illustrated that women taking NKO consumed significantly fewer analgesics during the 10-day treatment period than women receiving omega-3 fish oil (P < 0.03).
CONCLUSION: Neptune Krill Oil can significantly reduce dysmenorrhea and the emotional symptoms of premenstrual syndrome and is shown to be significantly more effective for the complete management of premenstrual symptoms compared to omega-3 fish oil.
Altern Med Rev. 2003 May;8(2):171-9. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea.
Cranberry Juice Reduces Urinary Tract Infection
Objective. —To determine the effect of regular intake of cranberry juice beverage on bacteriuria and pyuria in elderly women.
Design. —Randomized, double-blind, placebo-controlled trial.
Subjects. —Volunteer sample of 153 elderly women (mean age, 78.5 years).
Intervention. —Subjects were randomly assigned to consume 300 mL per day of a commercially available standard cranberry beverage or a specially prepared synthetic placebo drink that was indistinguishable in taste, appearance, and vitamin C content but lacked cranberry content.
Outcome Measures. —A baseline urine sample and six clean-voided study urine samples were collected at approximately 1-month intervals and tested quantitatively for bacteriuria and the presence of white blood cells.
Results. —Subjects randomized to the cranberry beverage had odds of bacteriuria (defined as organisms numbering ≥105/mL) with pyuria that were only 42% of the odds in the control group (P=.004). Their odds of remaining bacteriuric-pyuric, given that they were bacteriuric-pyuric in the previous month, were only 27% of the odds in the control group (P=.006).
Conclusions. —These findings suggest that use of a cranberry beverage reduces the frequency of bacteriuria with pyuria in older women. Prevalent beliefs about the effects of cranberry juice on the urinary tract may have microbiologic justification.
Vitamin B Reduces PMS
Summary: In a nested, case-control study involving 1,057 women with PMS and 1,968 controls, intakes of thiamine and riboflavin from food sources were found to be inversely associated with incident PMS. Women in the highest quintile of riboflavin intake 2-4 years prior to the year of diagnosis/assessment were found to have a 35% lower risk of developing PMS, as compared to those in the lowest quintile (RR=0.65). The authors conclude, "Further research is needed to evaluate the effects of B vitamins in the development of premenstrual syndrome."
Reference: "Dietary B vitamin intake and incident premenstrual syndrome," Chocano-Bedoya PO, Manson JE, et al, Am J Clin Nutr, 2011 Feb 23; [Epub ahead of print]. (Address: Departments of Public Health and Nutrition, Harvard School of Public Health, Boston, MA, USA).
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Nutrients and Diet
Alpha Lipoic Acid Amino Acids Antioxidants Arginine Calcium Carnitine Carotene Chromium Picolinate Citrulline Coenzyme Q10 DHEA Fat Fiber Fruit and Vegetables Garlic Ginkgo Biloba Glucosamine Vegetarian Diet Green Tea Iron Lutein Lycopene Magnesium Mediterranean Diet Multivitamins Nitric Oxide Nuts Olives Omega 3 Fatty Acids Policosanols Polyphenols Pomegranate Probiotics Pycnogenol Red Yeast Rice Salt Saffron Selenium Soy Theanine Vitamin A Vitamin B Vitamin C Vitamin D Vitamin E Vitamin K White Tea Zinc